Are there chitin- or chitosan-specific antibodies?

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Both chitin and, especially, chitosans appear to be rather poor antigens so that it is difficult to raise antibodies against them, but both polyclonal and monoclonal antibodies against chitosan have been raised successfully. These have been used for the cytochemical detection of chitosans, along with artificial chitosan-specific 'lectins' such as a fusion protein consisting of an inactivated chitosanase with fluorescent proteins such as GFP or YFP, or polyanionic oligogalacturonides as probes for the cytochemical detection chitosan. The fact that chitin and chitosans are so poorly antigenic makes these polymers highly biocompatible, and this is also the reason why they are not allergenic.